diff --git a/integration/fixtures/headers/remove_reverseproxy_headers.toml b/integration/fixtures/headers/remove_reverseproxy_headers.toml
new file mode 100644
index 000000000..48ce504cf
--- /dev/null
+++ b/integration/fixtures/headers/remove_reverseproxy_headers.toml
@@ -0,0 +1,31 @@
+[global]
+  checkNewVersion = false
+  sendAnonymousUsage = false
+
+[log]
+  level = "DEBUG"
+
+[entryPoints]
+  [entryPoints.web]
+    address = ":8000"
+
+[providers.file]
+  filename = "{{ .SelfFilename }}"
+
+## dynamic configuration ##
+
+[http.routers]
+  [http.routers.router1]
+    rule = "Host(`test.localhost`)"
+    middlewares = ["remove"]
+    service = "service1"
+
+[http.middlewares]
+  [http.middlewares.remove.headers.customRequestHeaders]
+    X-Forwarded-For = ""
+    Foo = ""
+
+[http.services]
+  [http.services.service1.loadBalancer]
+    [[http.services.service1.loadBalancer.servers]]
+      url = "http://127.0.0.1:9000"
diff --git a/integration/headers_test.go b/integration/headers_test.go
index 6e4b7e9b9..049783d85 100644
--- a/integration/headers_test.go
+++ b/integration/headers_test.go
@@ -1,7 +1,9 @@
 package integration
 
 import (
+	"net"
 	"net/http"
+	"net/http/httptest"
 	"os"
 	"time"
 
@@ -25,6 +27,46 @@ func (s *HeadersSuite) TestSimpleConfiguration(c *check.C) {
 	c.Assert(err, checker.IsNil)
 }
 
+func (s *HeadersSuite) TestReverseProxyHeaderRemoved(c *check.C) {
+	file := s.adaptFile(c, "fixtures/headers/remove_reverseproxy_headers.toml", struct{}{})
+	defer os.Remove(file)
+	cmd, display := s.traefikCmd(withConfigFile(file))
+	defer display(c)
+
+	err := cmd.Start()
+	c.Assert(err, checker.IsNil)
+	defer s.killCmd(cmd)
+
+	handler := http.HandlerFunc(func(w http.ResponseWriter, r *http.Request) {
+		_, found := r.Header["X-Forwarded-Host"]
+		c.Assert(found, checker.True)
+		_, found = r.Header["Foo"]
+		c.Assert(found, checker.False)
+		_, found = r.Header["X-Forwarded-For"]
+		c.Assert(found, checker.False)
+	})
+
+	listener, err := net.Listen("tcp", "127.0.0.1:9000")
+	c.Assert(err, checker.IsNil)
+
+	ts := &httptest.Server{
+		Listener: listener,
+		Config:   &http.Server{Handler: handler},
+	}
+	ts.Start()
+	defer ts.Close()
+
+	req, err := http.NewRequest(http.MethodGet, "http://127.0.0.1:8000/", nil)
+	c.Assert(err, checker.IsNil)
+	req.Host = "test.localhost"
+	req.Header = http.Header{
+		"Foo": {"bar"},
+	}
+
+	err = try.Request(req, 500*time.Millisecond, try.StatusCodeIs(http.StatusOK))
+	c.Assert(err, checker.IsNil)
+}
+
 func (s *HeadersSuite) TestCorsResponses(c *check.C) {
 	file := s.adaptFile(c, "fixtures/headers/cors.toml", struct{}{})
 	defer os.Remove(file)
diff --git a/pkg/middlewares/headers/header.go b/pkg/middlewares/headers/header.go
index 7c5a99af5..8e48f9f33 100644
--- a/pkg/middlewares/headers/header.go
+++ b/pkg/middlewares/headers/header.go
@@ -10,6 +10,7 @@ import (
 
 	"github.com/traefik/traefik/v2/pkg/config/dynamic"
 	"github.com/traefik/traefik/v2/pkg/log"
+	"github.com/vulcand/oxy/v2/forward"
 )
 
 // Header is a middleware that helps setup a few basic security features.
@@ -70,6 +71,10 @@ func (s *Header) modifyCustomRequestHeaders(req *http.Request) {
 	// Loop through Custom request headers
 	for header, value := range s.headers.CustomRequestHeaders {
 		switch {
+		// Handling https://github.com/golang/go/commit/ecdbffd4ec68b509998792f120868fec319de59b.
+		case value == "" && header == forward.XForwardedFor:
+			req.Header[header] = nil
+
 		case value == "":
 			req.Header.Del(header)
 
diff --git a/pkg/middlewares/headers/header_test.go b/pkg/middlewares/headers/header_test.go
index fa21fe311..363b7e737 100644
--- a/pkg/middlewares/headers/header_test.go
+++ b/pkg/middlewares/headers/header_test.go
@@ -29,11 +29,14 @@ func TestNewHeader_customRequestHeader(t *testing.T) {
 			desc: "delete a header",
 			cfg: dynamic.Headers{
 				CustomRequestHeaders: map[string]string{
+					"X-Forwarded-For":         "",
 					"X-Custom-Request-Header": "",
 					"Foo":                     "",
 				},
 			},
-			expected: http.Header{},
+			expected: http.Header{
+				"X-Forwarded-For": nil,
+			},
 		},
 		{
 			desc: "override a header",